產(chǎn)品詳情
中文同義詞:酮替芬延胡索酸;富馬酸酮替芬價(jià)格;酮替芬延胡索酸,99%;富馬酸酮替芬(標(biāo)準(zhǔn)品);甲哌噻庚酮;克脫吩;哌啶環(huán)庚酮;噻喘酮
英文名稱(chēng):Ketotifen fumarate
英文同義詞:Ketotifene fumarate;10H-Benzo4,5cyclohepta1,2-bthiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-, (2E)-2-butenedioate (1:1);zaditor;KETOTIFEN FUMARATE EP;4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one fumarate;Allerkif;Anatifen;Ketotifen Hydrogen FuMarate, EP
分子量: 425.5
EINECS號(hào):252-100-0
熔點(diǎn) 192 C
儲(chǔ)存條件 Store at RT
水溶解性 Soluble in water (10 mg/ml), DMSO (100 mM), and methanol.
最大波長(zhǎng)(λmax) 297nm(MeOH)(lit.)
Merck 14,53075
標(biāo)準(zhǔn):EP
天然/合成:合成
級(jí)別:醫(yī)藥級(jí)
含量:99%
外觀(guān):白色粉狀
包裝:1KG/聽(tīng) 可拆分
成份:4,9-二氫-4-(1-甲基-4-亞哌啶基)-10H-苯并[4,5]環(huán)庚[1,2-b]噻吩-10-酮反丁烯二酸鹽
理化屬性:類(lèi)白色結(jié)晶性粉末;無(wú)臭,味苦。本品在甲醇中溶解,在水或乙醇中微溶,在丙酮或三氯甲烷中極微溶解。
類(lèi)別:API
行業(yè):醫(yī)藥
領(lǐng)域:抗組胺
下延產(chǎn)品:(1)富馬酸酮替芬口服溶液 (2)富馬酸酮替芬片 (3)富馬酸酮替芬膠囊 (4)富馬酸酮替芬滴鼻液
運(yùn)用:用于蕁麻疹、瘙癢癥、濕疹、過(guò)敏性皮炎、特應(yīng)性皮炎、神經(jīng)性皮炎等過(guò)敏性疾病;近期報(bào)道治療硬皮病有效,對(duì)支氣管哮喘有很好的療效,對(duì)過(guò)敏性哮喘療效顯著,混合型次之,感染型約半數(shù)有效,對(duì)哮喘有預(yù)防作用
副作用:The biggest side effect of ketotefen is somnolence or fatigue and weakness. This side effect is more obvious in adults and is one of the main reasons for the limitation of clinical use. The somnolence or fatigue can reduce the living quality of asthma and children's asthma. Usually, after 1-4 weeks of continuous administration, the side effects of central nerve suppression can be significantly reduced or even gradually disappeared. The clinical observation showed that the combination of theophylline and theophylline could reduce the central nervous inhibition of ketotefen, and counteract the central nerve excitability of theophylline, but the synergistic anti-inflammatory effect needed further observation. Clinical observations confirm that children usually do not have a significant central neurologic inhibitory effect on ketotefen, which can only cause inattention in children. Even if the dose is given to adults, the mechanism is not b. Wood and other clinical observations of two years of continuous oral administration of asthma and children's asthma confirmed that the long-term use of ketotefen did not have other serious side effects and had no effect on the liver, renal function and peripheral blood cell count, and it was not susceptible to resistance. Generally, after six weeks of continuous oral Administration of fumaric acid ketotefen, it could start to compete. Bronchial spasmodic or glucocorticoids were gradually reduced, and no rebound phenomenon was observed after long term treatment. Therefore, the comprehensive buation of the drug is that ketotefen is a kind of central nervous inhibition (the side effect can be adapted gradually), relatively safe and effective, with a certain anti inflammatory properties, low price antiasthmatic drugs. Since FDA has not been approved so far, it should be used cautiously in clinical practice.
問(wèn):你們是生產(chǎn)廠(chǎng)家么?
答:是的,本公司除了生產(chǎn)本產(chǎn)品以外,公司廠(chǎng)里還生產(chǎn)他達(dá)那非,氨基他達(dá)那非,去甲基他達(dá)那非,伐地那非,阿伐那非,匹可硫酸鈉,呋塞米,布美他尼,氯霉素,克霉唑,硝酸咪康唑,鹽酸特比萘芬等原料藥,公司實(shí)驗(yàn)室也出品一些小分子靶向產(chǎn)品及原料,如克唑替尼,西地尼布,3922,INC280,曲美替尼、比馬前列素,拉坦前列素,曲安西龍衍生物,曲安奈德衍生物,甲硝唑衍生物,酮康唑類(lèi)似物,烏芬奈索等等原料。
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答:一般情況下我們產(chǎn)品都是有庫(kù)存的。與此同時(shí),衡陽(yáng)錦億,立足于華南,同時(shí)聯(lián)合華東,華中,華北的市場(chǎng)情況和市場(chǎng)份額,打造出了一套專(zhuān)業(yè)、高效、現(xiàn)代化的物流體系,可輕松實(shí)現(xiàn)從克級(jí)到噸級(jí)的物流要求。輕松實(shí)現(xiàn)當(dāng)天下單,當(dāng)天發(fā)貨,第二天到貨的戰(zhàn)略目的,為廣大客戶(hù)在使用上縮短時(shí)間節(jié)約成本。
問(wèn):怎么儲(chǔ)存?
答:干燥處保存,避免強(qiáng)光與高溫。
問(wèn):有效期多長(zhǎng)
答:24個(gè)月。
問(wèn):多少量起訂?
答:可自由選擇訂購(gòu)量,詳細(xì)咨詢(xún)銷(xiāo)售人員。
問(wèn):什么包裝?
答:藥采用雙層包裝,內(nèi)層用透明自封袋,外層為鋁箔袋。
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問(wèn):你們?cè)霞兌榷嗌伲?br /> 答:純度99%以上。
問(wèn):怎么付款?
答:款到發(fā)貨。
問(wèn):什么時(shí)候發(fā)貨?
答:工作時(shí)間周一至周五,14點(diǎn)前付款,可到當(dāng)天發(fā)貨。14點(diǎn)后付款次日發(fā)貨。我公司按國(guó)家法定假期休息,周六日只接受詢(xún)問(wèn)和下單,不發(fā)貨。
問(wèn):什么時(shí)候可以到貨?
答:正常情況下,省內(nèi)1-2日到達(dá),省外3-5天到達(dá)。(還有什么其他問(wèn)題,可以直接聯(lián)系馮經(jīng)理)